Species interactions are fundamental ecological forces that can have significant impacts on the evolutionary trajectories of species.Nonetheless, the contribution of predator-prey interactions to genetic and phenotypic divergence remains largely unknown.Predatory marine snails of the family Conidae exhibit specializations for different prey items a
The Mediator subunit MDT-15 confers metabolic adaptation to ingested material.
In eukaryotes, RNA polymerase II (Pol(II)) dependent gene expression requires accessory factors termed transcriptional coregulators.One coregulator that universally contributes to Pol(II)-dependent transcription is the Mediator, a multisubunit complex that is targeted by many transcriptional regulatory factors.For example, the Caenorhabditis elegan
Vacuolin-1 enhances RA-induced differentiation of human myeloblastic leukemia cells: evidence for involvement of a CD11b/FAK/LYN/SLP-76 axis subject to endosomal regulation that drives late differentiation steps
Abstract Background Retinoic acid(RA), an embryonic morphogen, regulates cell differentiation.Endocytosis regulates receptor signaling that governs such RA-directed cellular processes.Vacuolin-1 is Evening Primrose Oil/GLA a small molecule that disrupts endocytosis, motivating interest in its effect on RA-induced differentiation/arrest.In HL-60 mye
Dog and human neural sensitivity to voicelikeness: A comparative fMRI study
Voice-sensitivity in the auditory cortex of a range of mammals has been proposed to be determined primarily by tuning to conspecific auditory stimuli, but recent human findings indicate a role for a more general tuning to voicelikeness.Vocal emotional valence, a central characteristic of vocalisations, has been linked to the same basic acoustic par
Human Metabolic Enzymes Deficiency: A Genetic Mutation Based Approach
One of the extreme challenges in biology is to ameliorate the understanding of the mechanisms which emphasize metabolic enzyme deficiency (MED) and how these pretend to have influence on human health.However, it has been manifested that MED could be either inherited as inborn error of metabolism (IEM) or acquired, which carries a Thermometer Probe